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2018-02-12
"Environmental adaptation of Acanthamoeba castellanii and Entamoeba histolytica at genome level as seen by comparative genomic analysis" Shabardina et al. has been published by Int. J. Biol. Sci.
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2018-02-05
"Loss-of-function uORF mutations in human malignancies" by Schulz et al. has been published by Scientific Reports
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2018-01-15
Welcome Jonas Bohn to our institute!
2018-01-04
"Transcriptional interference by small transcripts in proximal promoter regions" by Pande et al. has been published by Nucleic Acids Research.
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2017-12-29
"The emerging picture of the mitochondrial protein import complexes of Amoebozoa supergroup" by Wojtkowska, Buczek et al. has been published by BMC Genomics.
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2017-09-05
Juan Manuel Galvez, welcome to our institute!
2017-09-05
Julian-Hendrik Matschke, welcome to our institute!
2017-07-11
Congratulations Philipp Fervers for for the successful defense of his doctoral thesis.
2017-07-24
Yukie Kashima, welcome to our institute!
2017-07-11
"Inferring clonal structure in HTLV-1-infected individuals: towards bridging the gap between analysis and visualization” by Farmanbar et al. has bee published by Human Genomics.
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2017-07-03
Welcome Reza Halabian, our new PhD student..
2017-06-27
"Sequencing and phasing cancer mutations in lung cancers using a long-read portable sequencer” by Suzuki et al. has bee published by DNA Research.
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2017-06-14
"Serotyping dengue virus with isothermal amplification and a portable sequencer.” by Yamagishi at al. has been published by Scientific Reports.
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Origin and evolution of mammalian overlapping genes

Overlapping genes in mammalian genomes are unexpected phenomena even though hundreds of pairs of protein coding overlapping genes have been reported so far. Overlapping genes can be divided into different categories based on genes orientation and parts being shared between overlapping genes. The biologic functions of natural antisense transcripts, their involvement in physiological processes and gene regulation in living organisms are not fully understood. Number of documented examples indicates that they may exert control at various levels of gene expression, such as transcription, mRNA processing, splicing, stability, transport, and translation. Similarly, evolutionary origin of such genes is not known, existing hypotheses can explain only selected cases of mammalian gene overlaps which could originate as result of rearrangements, overprinting, and/or adaption of signals in the neighboring gene locus.

2012-11-19 14:06